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RX Performance

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Calm, deep sleep

Fall asleep and stay asleep, without the next-day fog.

Sleep3 compounds

  1. 01

    Seltorexant

    Human data

    Quiets the 'stay awake' signal so you fall asleep without heavy sedation.

    What it isAn experimental drug from Johnson & Johnson that blocks only the orexin-2 receptor, the part of the wake system most tied to sleep and mood.

    Still in clinical trials and not approved anywhere yet.

    Full page in the Vault

  2. 02

    Picamilon

    Limited human data

    Takes the edge off a racing mind before bed.

    What it isGABA bonded to niacin, approved in Russia as a way to get GABA into the brain.

    Human data is mostly Russian. Not a legal dietary supplement in the US.

    Full page in the Vault

  3. 03

    Selank

    Limited human data

    Calms the anxiety that keeps you up, without sedating you.

    What it isA Russian anti-anxiety peptide (a tuftsin analogue), usually used as a nasal spray.

    Human data is small and mostly Russian.

    Full page in the Vault

Sleep basics first: same wake time, no screens late, cool dark room. These help on top of that, not instead of it.

These are compounds to research, not a protocol to copy. Education and my opinion, not medical advice. Talk to a doctor, especially before combining anything with prescription medication. Shop links are affiliate links: tapping one opens the store and copies my code.

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