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01Bm
BAM15
Animal data
Raises how much energy you burn at rest. In mice it caused fat loss without eating less.
What it isA mitochondrial uncoupler: it makes your cells burn fuel as heat instead of storing it.
No human trials. It is in the same class as DNP, which has killed people through overheating; BAM15 looked far safer in mice, but that is not proof for people. Stop if you run hot or sweat at rest, and never combine it with other uncouplers.
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02At
ATX-304
Limited human data
Mimics part of the effect of cardio: more fat and sugar burned, and a higher resting metabolic rate.
What it isAn AMPK activator (also called O304) in development for obesity. AMPK is the switch your body flips during exercise.
An early human study in people with obesity found less liver and belly fat and a higher resting metabolic rate. Bigger trials are still running.
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03Sl
SLU-PP-915
Animal data
More endurance and more fat burned for fuel, in mice.
What it isAn "exercise mimetic" that switches on ERR receptors, the genes that build endurance. It is the newer, oral successor to SLU-PP-332.
Animal data only. Banned in tested sport.
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04Sn
SANA (MVD1)
Limited human data
Makes fat cells burn energy as heat. It caused weight loss in mice, and a first human study has been published.
What it isAn experimental weight-loss compound (a salicylate derivative) from Eolo Pharma.
Very new. Human data is one small early study.
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05Al
Albuterol
Limited human dataPrescription drug
Raises energy use a little and helps hold muscle in a deficit.
What it isAn asthma drug (a beta-2 agonist) that some people use off-label to burn more fat. It is a milder relative of clenbuterol.
Prescription drug. Raises heart rate, causes shakiness and can lower potassium. Avoid with heart problems, high blood pressure, or on top of stimulants such as Adderall.
None of these replace a calorie deficit and protein. They make a cut easier; they do not do it for you. Start one at a time, and stop if you feel hot, shaky or your heart races.
These are compounds to research, not a protocol to copy. Education and my opinion, not medical advice. Talk to a doctor, especially before combining anything with prescription medication. Shop links are affiliate links: tapping one opens the store and copies my code.
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